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cotP [2019-09-04 10:47:41]
function
resistance of the spore
product
inner spore coat protein
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.5|Class V]Gene
Coordinates
601,741 602,172
The protein
Protein family
[SW|small heat shock protein (Hsp20) family] (according to UniProt)[SW|Localization]
inner spore coat, localization depends on [protein|CEBEC9CECCF445C40D793E61A2CD23175631A473|SafA] [Pubmed|22171814]Expression and Regulation
Operons
genes
[gene|68E585F6670539982E8E8032337DA2043C67FCC4|ydgB]-[gene|483587EB658850D786C3C95C02D419994FCC9F45|ydgA]-[gene|8F85E6DE353F29759301A463335BFC15F829E2D0|cotP]
description
[Pubmed|22383849]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK]: sigma factor, [Pubmed|15699190], in [regulon|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK regulon]regulatory mechanism
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|GerE]: repression, [Pubmed|9068633], in [regulon|19228BAD44E6DA3DE908DC390FDF628C18D94E65|GerE regulon]regulation
expressed during sporulation ([protein|6FAD8804AA32B84819DDE57C0AF63F208FB9FFD1|SigKC]) [Pubmed|15699190]view in new tabBiological materials
Mutant
MGNA-C172 (ydfT::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2170 NBRP B. subtilis, Japan]BKE05550 ([gene|8F85E6DE353F29759301A463335BFC15F829E2D0|cotP]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE05550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGAGATTCTCCTTAAA, downstream forward: _UP4_GGGCTTTAAGATTGATTGTTBKK05550 ([gene|8F85E6DE353F29759301A463335BFC15F829E2D0|cotP]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK05550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGAGATTCTCCTTAAA, downstream forward: _UP4_GGGCTTTAAGATTGATTGTTReferences
11150673,15699190,9068633,22171814,26187959